Pseudoephedrine from cold medicine, extraction method.

[hacke8]

Hello fellow chemists. Today I brought a cold medicine (capsule) containing pseudoephedrine hydrochloride. There are 8 capsules in a box. Each capsule contains 90 mg of pseudoephedrine, totaling 0.72 grams. It is very cheap at US$1.5. Here are its ingredients: Each capsule contains 90 mg of pseudoephedrine hydrochloride. mg, chlorpheniramine maleate (chlorpheniramine) 4 mg. The auxiliary materials are: starch, sucrose, hydroxypropyl methylcellulose, ethyl cellulose polymer, Opadry yellow dry spray material, Opadry pink dry spray material. How can I maximize extraction?
My own extraction steps are: open the capsule - soak in 99% ethanol - suction filtration - evaporate the filtrate to the extract - add cold water to the extract (glue will appear) - suction filtration - adjust the filtrate to alkali PH12+ and then extract, (xylene ) Dry the extract - after drying, pass in hydrogen chloride gas (the pH reaches acidity) - filter with suction to obtain white pseudoephedrine hydrochloride powder. But I tried several extractions and only got very little pseudoephedrine. Is there any way to increase the yield?

 

[hacke8]

@G.Patton
Sir, please help me find out the problem. The yield is too low.

 

[G.Patton]

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/ephedrine-extraction-from-pills-methods.2443/

Hi, try the second method with toluene instead of xylene.

Each capsule contains 90 mg of pseudoephedrine, totaling 0.72 grams.

hacke8how much did you get?

 

[hacke8]

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/ephedrine-extraction-from-pills-methods.2443/

Hi, try the second method with toluene instead of xylene.

how much did you get?

G.PattonHi, sir, I got a 40% yield according to my method. In the second way, I can't buy naphtha.